| Initiative | City | State |
|---|---|---|
| Alabama Operations Center Major Investigations Team | Montgomery | Alabama |
| BLOC/HIDTA Watch Center | Gulfport | Mississippi |
| Caddo/Bossier Drug Task Force | Shreveport | Louisiana |
| Investigative Support Center | Metairie | Louisiana |
| Jackson County Major Investigations Team | Pascagoula | Mississippi |
| Jefferson County HIDTA Drug Task Force | Birmingham | Alabama |
| Metropolitan New Orleans Major Investigations Team | Metairie | Louisiana |
| City of New Orleans Major Investigation Team | Metairie | Louisiana |
| Metropolitan New Orleans Mobile Deployment Team | New Orleans | Louisiana |
| North Alabama Drug Task Force | Huntsville | Alabama |
| Management and Coordination | Metairie | Louisiana |
| Multi-Agency Safe Neighborhoods (MASN)/Multi Agency Gang (MAG) Task Force | METAIRIE | Louisiana |
| Middle Louisiana Major Investigations Team/Transportation Interdiction Group | Baton Rouge | Louisiana |
| Mobile Baldwin Counties Major Investigations Team | Mobile | Alabama |
| Monroe Metro Drug Task Force | West Monroe | Louisiana |
| Metro Jackson Major InvestigationsTeam | Jackson | Mississippi |
| Metro Jackson Mobile Deployment Team | Pearl | Mississippi |
| New Orleans Gang Task Force | New Orleans | Louisiana |
| North Mississippi Major Investigations Team | Oxford | Mississippi |
| Northwest Louisiana Violent Crimes Task Force | Shreveport | Louisiana |
| Project Star | Harvey | Louisiana |
| Southwest Louisiana Major Investigations Team | Lafayette | Louisiana |
| Tri County Major Investigations Team | Gulfport | Mississippi |
| Calcasieu Parish CAT (Combined Anti-Drug Team) | Lake Charles | Louisiana |
| Little Rock Major Investigations/Mobile Deployment Teams | Little Rock | Arkansas |
| US Marshals Service Fugitive Task Force | North Little Rock | Arkansas |
| Northwest Arkansas Major Investigations/Mobile Deployment Teams | Fayetteville | Arkansas |
| Western Arkansas Mobile Deployment Team | Fayetteville | Arkansas |
| Shelby County HIDTA Task Force | Memphis | Tennessee |
| Forrest County Major Investigations Team | Hattiesburg | Mississippi |
| Shelby County Multi-Agency Gang Unit (MGU) | Memphis | Tennessee |
| Border Enforcement Security Task Force (BEST) | Hammond | Louisiana |
| Homeland Security Investigations Task Force | Fayetteville | Arkansas |
| Mississippi Gulf Coast Border Enforcement Security Task Force | Biloxi | Mississippi |
| Mobile/Baldwin Border Enforcement SecurityTaskForce | Mobile | Alabama |
| NW Florida Drug Task Force | Pensacola | Florida |
| Border Enforcement Security Task Force West Tennessee | Memphis | Tennessee |
| Resource Initiative | Metairie | Louisiana |